Polyphenylene Dendrimers as Scaffolds for Shape-Persistent Multiple Peptide Conjugates
نویسندگان
چکیده
منابع مشابه
Polyphenylene dendrimers as scaffolds for shape-persistent multiple peptide conjugates.
The present work describes synthetic concepts for the coupling of peptides to polyphenylene dendrimers (PPDs). Novel functionalized cyclopentadienones have been synthesized whose Diels-Alder cycloaddition with various core molecules leads to polyphenylene dendrimers possessing (protected) amino or carboxyl groups. In addition, the resulting functionalized molecules exhibit the characteristic sh...
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A novel synthesis is presented of a fourfold ethynyl-substituted perylene diimide dye 4, which acts as a core molecule for the buildup of polyphenylene dendrimers. Around the luminescent core 4, a first-generation (5), a second-generation (6), and a third-generation (7) polyphenylene dendritic environment consisting of pentaphenylbenzene building blocks are constructed. The dendrimers 5 and 6 a...
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ژورنال
عنوان ژورنال: Bioconjugate Chemistry
سال: 2005
ISSN: 1043-1802,1520-4812
DOI: 10.1021/bc049839k